Mutation Rate Distribution Inferred from Coincident SNPs and Coincident Substitutions
نویسندگان
چکیده
منابع مشابه
Mutation Rate Distribution Inferred from Coincident SNPs and Coincident Substitutions
Mutation rate variation has the potential to bias evolutionary inference, particularly when rates become much higher than the mean. We first confirm prior work that inferred the existence of cryptic, site-specific rate variation on the basis of coincident polymorphisms-sites that are segregating in both humans and chimpanzees. Then we extend this observation to a longer evolutionary timescale b...
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ژورنال
عنوان ژورنال: Genome Biology and Evolution
سال: 2011
ISSN: 1759-6653
DOI: 10.1093/gbe/evr044